SSD or Graphics Card in the PCIE-3 Slot

the only issue that might arise is the air flow for a 3 slot GPU will put your fans really close to the glass since you can only verticallymount your gpu

B550M DS3H ; 1 Solid Pin Power Connector ; 2 DVI ; 3 DisplayPort + HDMI ; 4 Realtek GbE LAN ; 5 Ultra Durable PCIe Slot · PCIe® Slot · Running 1*

358 slot Product Thumbnail 3; Product Thumbnail 4 The advanced PCI-E Steel Slot packed with solid cover that prevent any signal interference with graphics cards

3 hot chillies slot Slot in GPU to Riser 2:27 IO Covers and GPU Lock Bar 3:20 Top StrutSpine 4:31 Side